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工作压力大有多可怕?-亚博首页

时期:2021-02-19 22:16 点击数:
本文摘要:New research shows just how stressful starting a new career as a doctor can be: stressful enough to have your DNA age six times faster than it normally would.一项新的研究强调,刚开始医生新的岗位的压力有多大:压力不能给你的DNA细胞凋亡速率比长期状况慢六倍。

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New research shows just how stressful starting a new career as a doctor can be: stressful enough to have your DNA age six times faster than it normally would.一项新的研究强调,刚开始医生新的岗位的压力有多大:压力不能给你的DNA细胞凋亡速率比长期状况慢六倍。Scientists studying cellular ageing through DNA telomeres (the tips of our chromosomes), which shrink as we get older, found that this natural shrinkage was happening at an accelerated rate among new doctors – the equivalent of six years worth of shortening in just 12 months.生物学家根据DNA端粒(性染色体的“顶尖”)研究细胞衰老,伴随着年纪的持续增长,端粒不容易澎涨。她们寻找,新的医生身体的这类自然界澎涨速率已经缓解——这相当于在短短的12个月内增加六年的時间。

Its the first large, longitudinal study to look at the link between chronic stress and cell ageing, and the team behind the research says it could have implications for those in any high-pressure situation, from trainee soldiers to new parents.它是第一个大中型的横着研究,偏重于漫性压力和细胞衰老中间的联络,研究精英团队答复,这很有可能会对一切髙压自然环境下的人造成危害,从新兵入伍到新的爸爸妈妈。Research has implicated telomeres as an indicator of ageing and disease risk, but these longitudinal findings advance the possibility that telomere length can serve as a biomarker that tracks effects of stress, says one of the team, neuroscientist and psychiatrist Srijan Sen from the University of Michigan (U-M).“研究强调端粒是细胞凋亡和病症风险性的一个指标值,但这种横着研究結果明确指出了端粒长短能够做为一种生物标志物来跟踪压力的危害的概率,”研究工作组组员之一、密歇根大学(University of Michigan)的神经学家和精神医学家斯里扬·森(Srijan Sen)讲到。It will be important to study how telomere changes play out in larger groups of medical trainees and in other groups of people subjected to specific prolonged stresses.“研究端粒转变怎样在更高范畴的医药学学习培训生人群和别的长时间承受特殊压力的群体中充分发挥,将是很最重要的。”The researchers took DNA samples from 250 new doctors at the start and end of their first intern year. These were compared to samples from 84 U-M freshmen students. In addition, the team measured the participants mental well-being and stress levels over time with the use of questionnaires throughout the year.研究工作人员从250名新的医生的身上提纯了DNA样版,这种医生全是在她们第一个学习本年度的刚开始和完成时进行的。

这种数据信息与84名密歇根大学新生儿的样版进行了比较。除此之外,研究工作组还根据全年度的调查问卷,精确测量了参加者的心里健康和压力水准。

Besides telomere attrition being six times greater in the doctors, some other interesting findings came to light – for example, the longer hours the new doctors worked, the faster their telomeres shrank.除开医生的“端粒损坏”是平常人的六倍以外,一些有趣的寻找也露出水面——比如,新的医生工作中的時间就会越宽,她们的端粒衰落得变慢。


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